Pretreatment with remifentanil protects against the reduced-intestinal contractility related to the ischemia and reperfusion injury in rat

SAYAN ÖZAÇMAK H., Ozacmak V. H., TURAN İ., BARUT F., Hancic V.

REVISTA BRASILEIRA DE ANESTESIOLOGIA, cilt.65, sa.6, ss.483-490, 2015 (SCI-Expanded) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 65 Sayı: 6
  • Basım Tarihi: 2015
  • Doi Numarası: 10.1016/j.bjan.2013.09.006
  • Dergi Adı: REVISTA BRASILEIRA DE ANESTESIOLOGIA
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Sayfa Sayıları: ss.483-490
  • Anahtar Kelimeler: Intestinal contractility, Intestinal ischemia/ reperfusion injury, Rat, Remifentanil, OPIOID-RECEPTOR ACTIVATION, K-ATP-CHANNELS, IN-VITRO, ISCHEMIA/REPERFUSION INJURY, INTERSTITIAL-CELLS, L-ARGININE, CARDIOPROTECTION, INFLAMMATION, SEVOFLURANE, MOTILITY
  • Dokuz Eylül Üniversitesi Adresli: Evet

Özet

Background and objectives: Serious functional and structural alterations of gastrointestinal tract are observed in failure of blood supply, leading to gastrointestinal dismotility. Activation of opioid receptors provides cardioprotective effect against ischemia-reperfusion (i/R) injury. The aim of the present study was to determine whether or not remifentanil could reduce i/R injury of small intestine.