Polycystic ovary syndrome is associated with increased osteopontin levels
EUROPEAN JOURNAL OF ENDOCRINOLOGY, vol.174, no.4, pp.415-423, 2016 (SCI-Expanded, Scopus)
- Publication Type: Article / Article
- Volume: 174 Issue: 4
- Publication Date: 2016
- Doi Number: 10.1530/eje-15-1074
- Journal Name: EUROPEAN JOURNAL OF ENDOCRINOLOGY
- Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
- Page Numbers: pp.415-423
- Open Archive Collection: AVESIS Open Access Collection
- Dokuz Eylül University Affiliated: Yes
Abstract
Objective: Osteopontin (OPN) is a multi-functional secreted glycoprotein that plays a crucial role in glucose metabolism and inflammatory process. Growing evidence suggests that there is a link between OPN and ovarian function. However, no such link has yet been found for OPN in polycystic ovary syndrome (PCOS). Our aim was to ascertain whether circulating OPN levels are altered in women with PCOS and to determine whether OPN levels differ between the follicular phase and mid-cycle of the menstrual cycle in eumenorrheic women.