Polycystic ovary syndrome is associated with increased osteopontin levels

Creative Commons License

Saklamaz A., Calan M., Yilmaz O., KÜME T., Temur M., Yildiz N., ...Daha Fazla

EUROPEAN JOURNAL OF ENDOCRINOLOGY, cilt.174, sa.4, ss.415-423, 2016 (SCI-Expanded) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 174 Sayı: 4
  • Basım Tarihi: 2016
  • Doi Numarası: 10.1530/eje-15-1074
  • Dergi Adı: EUROPEAN JOURNAL OF ENDOCRINOLOGY
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Sayfa Sayıları: ss.415-423
  • Dokuz Eylül Üniversitesi Adresli: Evet

Özet

Objective: Osteopontin (OPN) is a multi-functional secreted glycoprotein that plays a crucial role in glucose metabolism and inflammatory process. Growing evidence suggests that there is a link between OPN and ovarian function. However, no such link has yet been found for OPN in polycystic ovary syndrome (PCOS). Our aim was to ascertain whether circulating OPN levels are altered in women with PCOS and to determine whether OPN levels differ between the follicular phase and mid-cycle of the menstrual cycle in eumenorrheic women.