Copy For Citation
Arikan-Ayyildiz Z., KARAMAN M., Firinci F., KİRAY M., BAĞRIYANIK H. A., YILMAZ O., ...More
IRANIAN JOURNAL OF ALLERGY ASTHMA AND IMMUNOLOGY, vol.13, no.5, pp.317-323, 2014 (SCI-Expanded)
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Publication Type:
Article / Article
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Volume:
13
Issue:
5
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Publication Date:
2014
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Journal Name:
IRANIAN JOURNAL OF ALLERGY ASTHMA AND IMMUNOLOGY
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Journal Indexes:
Science Citation Index Expanded (SCI-EXPANDED), Scopus
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Page Numbers:
pp.317-323
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Keywords:
Acute asthma, Inflammation, L-arginine, Murine model, SaO(2), NITRIC-OXIDE SYNTHASE, AIRWAY INFLAMMATION, ARGINASE, ALLERGEN, SUPEROXIDE
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Dokuz Eylül University Affiliated:
Yes
Abstract
Increased arginase activity in the airways decreases L-arginine and causes deficiency of bronchodilating and anti-inflammatory nitric oxide (NO) in asthma. As, it is suggested that Larginine may have therapeutic potential in asthma treatment, we aimed to investigate the effects of inhaled L-arginine on oxygen saturation (SaO(2)) and airway histology in a murine model of acute asthma.