Effects of Inhaled L-Arginine Administration in A Murine Model of Acute Asthma
IRANIAN JOURNAL OF ALLERGY ASTHMA AND IMMUNOLOGY, cilt.13, sa.5, ss.317-323, 2014 (SCI-Expanded, Scopus)
- Yayın Türü: Makale / Tam Makale
- Cilt numarası: 13 Sayı: 5
- Basım Tarihi: 2014
- Dergi Adı: IRANIAN JOURNAL OF ALLERGY ASTHMA AND IMMUNOLOGY
- Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
- Sayfa Sayıları: ss.317-323
- Anahtar Kelimeler: Acute asthma, Inflammation, L-arginine, Murine model, SaO(2)
- Dokuz Eylül Üniversitesi Adresli: Evet
Özet
Increased arginase activity in the airways decreases L-arginine and causes deficiency of bronchodilating and anti-inflammatory nitric oxide (NO) in asthma. As, it is suggested that Larginine may have therapeutic potential in asthma treatment, we aimed to investigate the effects of inhaled L-arginine on oxygen saturation (SaO(2)) and airway histology in a murine model of acute asthma.