IRANIAN JOURNAL OF ALLERGY ASTHMA AND IMMUNOLOGY, vol.13, no.5, pp.317-323, 2014 (SCI-Expanded)
Article / Article
IRANIAN JOURNAL OF ALLERGY ASTHMA AND IMMUNOLOGY
Science Citation Index Expanded (SCI-EXPANDED), Scopus
Acute asthma, Inflammation, L-arginine, Murine model, SaO(2), NITRIC-OXIDE SYNTHASE, AIRWAY INFLAMMATION, ARGINASE, ALLERGEN, SUPEROXIDE
Dokuz Eylül University Affiliated:
Increased arginase activity in the airways decreases L-arginine and causes deficiency of bronchodilating and anti-inflammatory nitric oxide (NO) in asthma. As, it is suggested that Larginine may have therapeutic potential in asthma treatment, we aimed to investigate the effects of inhaled L-arginine on oxygen saturation (SaO(2)) and airway histology in a murine model of acute asthma.