Improvement of colonic healing by preoperative oral partially hydrolyzed guar gum (Benefiber) in rats which underwent preoperative radiotherapy


SEVİNÇ A. İ., Aydogan B., Canda A. E., ÇETİNAYAK H. O., Terzi C., Oktay G., ...More

JOURNAL OF DRUG TARGETING, vol.22, no.3, pp.262-266, 2014 (SCI-Expanded, Scopus)

  • Publication Type: Article / Article
  • Volume: 22 Issue: 3
  • Publication Date: 2014
  • Doi Number: 10.3109/1061186x.2013.866674
  • Journal Name: JOURNAL OF DRUG TARGETING
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Page Numbers: pp.262-266
  • Keywords: Anastomosis, Benefiber, healing, radiotherapy
  • Dokuz Eylül University Affiliated: Yes

Abstract

Background: Neoadjuvant radiotherapy in rectal cancer could interfere with anastomotic healing. We investigated the effects of preoperative oral administration of Benefiber on the healing irradiated colonic anastomosis.