Chronic recurrent multifocal osteomyelitis in a patient with selective immunoglobulin M deficiency

Makay B., Unsal E., Anal O., Gunes D., Men S., Cakmakci H., ...More

RHEUMATOLOGY INTERNATIONAL, vol.29, no.7, pp.811-815, 2009 (SCI-Expanded) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 29 Issue: 7
  • Publication Date: 2009
  • Doi Number: 10.1007/s00296-008-0788-0
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Page Numbers: pp.811-815
  • Keywords: Chronic recurrent multifocal osteomyelitis, Selective IgM deficiency, IGM DEFICIENCY, SAPHO SYNDROME, PROPIONIBACTERIUM-ACNES, LYMPHOCYTES, OSTEITIS, CHILDREN
  • Dokuz Eylül University Affiliated: Yes


Chronic recurrent multifocal osteomyelitis is an unusual inflammatory process of unknown origin involving multiple osseous sites, often recurrently. Selective immunoglobulin M (IgM) deficiency is a rare primary immunodeficiency disease, which can be associated with autoimmune diseases such as systemic lupus erythematosus, Hashimoto's disease, or hemolytic anemia. Here we report a case of a chronic recurrent multifocal osteomyelitis coexisting with selective IgM deficiency.