The ALBI grade provides objective hepatic reserve estimation across each BCLC stage of hepatocellular carcinoma
JOURNAL OF HEPATOLOGY, vol.66, no.2, pp.338-346, 2017 (SCI-Expanded, Scopus)
- Publication Type: Article / Article
- Volume: 66 Issue: 2
- Publication Date: 2017
- Doi Number: 10.1016/j.jhep.2016.09.008
- Journal Name: JOURNAL OF HEPATOLOGY
- Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
- Page Numbers: pp.338-346
- Keywords: Prognosis, Carcinoma, Hepatocellular, Liver failure, ALBI, Albumins, Bilirubin, Retrospective studies, Biomarkers
- Open Archive Collection: AVESIS Open Access Collection
- Dokuz Eylül University Affiliated: Yes
Abstract
Background & Aims: Overall survival (OS) is a composite clinical endpoint in hepatocellular carcinoma (HCC) due to the mutual influence of cirrhosis and active malignancy in dictating patient's mortality. The ALBI grade is a recently described index of liver dysfunction in hepatocellular carcinoma, based solely on albumin and bilirubin levels. Whilst accurate, this score lacks cross validation, especially in intermediate stage HCC, where OS is highly heterogeneous.