Remember Diabetes Mellitus When Assessing Renal Blood Flow in Hypertensive Patients: A Renal Frame Count Study


Cerik I. B., Dindas F., YILMAZ M. B.

TURK KARDIYOLOJI DERNEGI ARSIVI-ARCHIVES OF THE TURKISH SOCIETY OF CARDIOLOGY, cilt.51, sa.1, ss.32-39, 2023 (ESCI) identifier identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 51 Sayı: 1
  • Basım Tarihi: 2023
  • Doi Numarası: 10.5543/tkda.2022.77567
  • Dergi Adı: TURK KARDIYOLOJI DERNEGI ARSIVI-ARCHIVES OF THE TURKISH SOCIETY OF CARDIOLOGY
  • Derginin Tarandığı İndeksler: Emerging Sources Citation Index (ESCI), Scopus, Central & Eastern European Academic Source (CEEAS), Directory of Open Access Journals, TR DİZİN (ULAKBİM)
  • Sayfa Sayıları: ss.32-39
  • Anahtar Kelimeler: Diabetes mellitus, renal blood flow, renal frame count
  • Dokuz Eylül Üniversitesi Adresli: Evet

Özet

Objective: Diabetes mellitus (DM) progresses with dynamic changes in renal blood flow and glomerular filtration. Renal frame count (RFC) is a cineangiographical parameter that is capable of presenting microvascular and macrovascular changes in the renal blood flow. We aimed to show the changes, which may be caused by DM in the perfusion, by using RFC. Methods: A total of 110 hypertensive subjects consisting of 55 DM patients and 55 non-DM patients, as a control group who underwent renal angiography, were retrospectively enrolled in the study. The RFC values of all subjects were calculated and compared to each other. Results: There were no significant differences between the two groups in terms of basal de-mographic characteristics and antihypertensive medications. The RFC value measured from the left renal artery was significantly lower in the DM group compared to the control group (11.33 +/- 2.55, 13.49 +/- 3.24, respectively; P <0.001). The RFC value measured in the right renal artery was detected to be significantly lower in the DM group than in the control group (11.07 +/- 2.43, 13.33 +/- 3.07, respectively; P <0.001). The mean RFC value was also significantly lower in the DM group compared to the control group (11.20 +/- 2.18, 13.41 +/- 2.84, respectively; P <0.001). In the multivariable linear regression analysis conducted to determine the variables which may affect mean RFC, it was determined that only the HbA1C level had a relation with the mean RFC value. Conclusion: To the best of our knowledge, this is the first study to show the influence of DM on RFC. The RFC seems to decrease in DM subjects.