Total knee arthroplasty in ochronosis: a case report and critical review of the literature

Ozmanevra R., Guran O., Karatosun V. A., Gunal I.

EKLEM HASTALIKLARI VE CERRAHISI-JOINT DISEASES AND RELATED SURGERY, cilt.24, sa.3, ss.169-172, 2013 (SCI-Expanded) identifier identifier identifier

  • Yayın Türü: Makale / Derleme
  • Cilt numarası: 24 Sayı: 3
  • Basım Tarihi: 2013
  • Doi Numarası: 10.5606/ehc.2013.36
  • Dergi Adı: EKLEM HASTALIKLARI VE CERRAHISI-JOINT DISEASES AND RELATED SURGERY
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus, TR DİZİN (ULAKBİM)
  • Sayfa Sayıları: ss.169-172
  • Anahtar Kelimeler: Alkaptonuric ochronosis, knee replacement arthroplasty, ochronosis
  • Dokuz Eylül Üniversitesi Adresli: Evet

Özet

Alkaptonuria is an autosomal recessive disorder caused by the deficiency of homogentisate 1.2 dioxygenase activity. The clinical presentation shows an ochronotic pigment which is deposited in all connective tissues, including in cartilage, particularly. The knee is the most common site of peripheral abnormality. There is currently no definitive cure for alkaptonuric ochronosis. In this article, we present a 69-year-old male case who underwent bilateral cemented total knee arthroplasty simultaneously. Our results during two-year follow-up were satisfactory. A critical review of the literature revealed no uniformity in reporting such cases.