An extraneural primary anaplastic ependymoma at the subcutaneous inguinal region: Report of a rare case

Sayar H., Ersen A., KURTUL N., Yazar M. F., Balakan O.

INDIAN JOURNAL OF PATHOLOGY AND MICROBIOLOGY, vol.58, no.4, pp.560-562, 2015 (SCI-Expanded) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 58 Issue: 4
  • Publication Date: 2015
  • Doi Number: 10.4103/0377-4929.168883
  • Journal Name: INDIAN JOURNAL OF PATHOLOGY AND MICROBIOLOGY
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Page Numbers: pp.560-562
  • Keywords: Ependymoma, epithelial membrane antigen, extraneural tumor, glial fibrillary acidic protein, subcutaneous tumor, CENTRAL-NERVOUS-SYSTEM, CAVITY
  • Dokuz Eylül University Affiliated: Yes

Abstract

Ependymomas commonly arise in the central nervous system. Extraneural presentation is quite rare. Herein, we describe a primary extraneural ependymoma in a young female. The mass was located in the right inguinal area. The cut surface of the 7.5 mm x 6.5 mm x 4.5 mm sized tumor was brownish-yellow in color. Histologically, it was hypercellular exhibiting pseudorosette or rosette formations and some papillary structures. Mitosis was counted as high as 10 per 10 high power fields. Neither necrosis nor vascular endothelial proliferation within the tumor was observed. Tumor cells showed strong glial fibrillary acidic protein immunoreactivity. On epithelial membrane antigen, intracytoplasmic dot-like immunostaining was observed. This is the first report presenting a primary extraneural anaplastic ependymoma arising in the inguinal subcutaneous region.