Neuroanatomical correlates of genetic risk for bipolar disorder: A voxel-based morphometry study in bipolar type I patients and healthy first degree relatives

Saricicek, Aybala; Yalin, Nefize; HIDIROĞLU ONGUN, CEREN; Cavusoglu, Berrin; TAŞ, CUMHUR; Ceylan, Deniz; Zorlu, Nabi; ADA, EMEL; Tunca, Zeliha; Ozerdem, Aysegul

doi:10.1016/j.jad.2015.06.055

Neuroanatomical correlates of genetic risk for bipolar disorder: A voxel-based morphometry study in bipolar type I patients and healthy first degree relatives

Atıf İçin Kopyala

Saricicek A., Yalin N., HIDIROĞLU ONGUN C., Cavusoglu B., TAŞ C., Ceylan D., ...Daha Fazla

JOURNAL OF AFFECTIVE DISORDERS, cilt.186, ss.110-118, 2015 (SCI-Expanded)

Yayın Türü: Makale / Tam Makale
Cilt numarası: 186
Basım Tarihi: 2015
Doi Numarası: 10.1016/j.jad.2015.06.055
Dergi Adı: JOURNAL OF AFFECTIVE DISORDERS
Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Social Sciences Citation Index (SSCI), Scopus
Sayfa Sayıları: ss.110-118
Anahtar Kelimeler: Bipolar disorder, Voxel based morphometry, Endophenotype, Inferior frontal gyrus, Cerebellum, GRAY-MATTER VOLUME, INFERIOR FRONTAL GYRUS, BRAIN STRUCTURAL-CHANGES, PARAHIPPOCAMPAL CORTEX, RESPONSE-INHIBITION, LITHIUM TREATMENT, MRI ANALYSIS, ABNORMALITIES, SCHIZOPHRENIA, MEMORY
Dokuz Eylül Üniversitesi Adresli: Evet

Özet

Background: Bipolar disorder (BD) is a highly heritable mental illness which is associated with neuroanatomical abnormalities. Investigating healthy individuals at high genetic risk for bipolar disorder may help to identify neuroanatomical markers of risk and resilience without the confounding effects of burden of illness or medication.