The effect of carbamazepine treatment on serum leptin levels

Uludag I. F., Kulu U., Sener U., Kose Ş., Zorlu Y.

EPILEPSY RESEARCH, vol.86, no.1, pp.48-53, 2009 (SCI-Expanded) identifier identifier

  • Publication Type: Article / Article
  • Volume: 86 Issue: 1
  • Publication Date: 2009
  • Doi Number: 10.1016/j.eplepsyres.2009.04.005
  • Journal Name: EPILEPSY RESEARCH
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Page Numbers: pp.48-53
  • Keywords: Leptin, Carbamazepine, Insulin, Epilepsy, Weight gain, PLASMA LEPTIN, BODY-WEIGHT, VALPROATE, INSULIN, WOMEN, SEX, OBESE, TOPIRAMATE, HORMONES, ONSET
  • Dokuz Eylül University Affiliated: No

Abstract

Patients with epilepsy may manifest metabolic adverse effects throughout the course of their management with antiepileptic drugs. Leptin is a hormone that plays a major role in the regulation of feeding and energy expenditure. Leptin has been expected to form a link to weight gain in epilepsy with the use of some antiepileptic drugs. The aim of this study is to evaluate the effect of carbamazepine on body weight and serum leptin levels.