Study for the diagnostic screening of paroxsymal nocturnal hemoglobinuria in Turkey: Prospective multicentric evaluation of suspected patients

İLHAN, OSMAN; Ozdemir, Zehra; Ozet, Gulsum; Falay, Mesude; YENEREL, Mustafa; Tuglular, Tulin; Turgut, Mehmet; Guvenc, Birol; Unal, Ali; Ayyildiz, Orhan; Andic, Neslihan; Hacihanefioglu, Abdullah; Sahin, Fahri; Sencan, Mehmet; Ali, Ridvan; Ozsan, GÜNER; Yildirim, Rahsan; Tiftik, Eyup; Tombak, Aml; Salim, Ozan; Kaya, Emin; Akay, Olga; Okan, Vahap; Pehlivan, Mustafa; Saydam, Guray

doi:10.1016/j.transci.2019.08.021

Study for the diagnostic screening of paroxsymal nocturnal hemoglobinuria in Turkey: Prospective multicentric evaluation of suspected patients

Atıf İçin Kopyala

İLHAN O., Ozdemir Z. N., Ozet G., Falay M., YENEREL M. N., Tuglular T., ...Daha Fazla

TRANSFUSION AND APHERESIS SCIENCE, cilt.58, sa.5, ss.659-662, 2019 (SCI-Expanded)

Yayın Türü: Makale / Tam Makale
Cilt numarası: 58 Sayı: 5
Basım Tarihi: 2019
Doi Numarası: 10.1016/j.transci.2019.08.021
Dergi Adı: TRANSFUSION AND APHERESIS SCIENCE
Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
Sayfa Sayıları: ss.659-662
Anahtar Kelimeler: Paroxysmal nocturnal hemoglobinuria, Multiparameter flow cytometry, Diagnostic screening, SOMATIC MUTATION, PNH, COMPLEMENT, GUIDELINES, MANAGEMENT
Dokuz Eylül Üniversitesi Adresli: Evet

Özet

Background: Paroxysmal nocturnal hemoglobinuria (PNH) is a rare disease presenting with variable and various clinical findings. PNH might be overlooked and diagnosis may be delayed due to low awareness about PNH. This is the first multicenter study in Turkey, investigating the efficiency of diagnostic screening of PNH by multiparameter flow cytometry (FCM) according to consensus guidelines.