Study for the diagnostic screening of paroxsymal nocturnal hemoglobinuria in Turkey: Prospective multicentric evaluation of suspected patients

İLHAN O., Ozdemir Z. N., Ozet G., Falay M., YENEREL M. N., Tuglular T., ...More

TRANSFUSION AND APHERESIS SCIENCE, vol.58, no.5, pp.659-662, 2019 (SCI-Expanded) identifier identifier

  • Publication Type: Article / Article
  • Volume: 58 Issue: 5
  • Publication Date: 2019
  • Doi Number: 10.1016/j.transci.2019.08.021
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Page Numbers: pp.659-662
  • Keywords: Paroxysmal nocturnal hemoglobinuria, Multiparameter flow cytometry, Diagnostic screening, SOMATIC MUTATION, PNH, COMPLEMENT, GUIDELINES, MANAGEMENT
  • Dokuz Eylül University Affiliated: Yes


Background: Paroxysmal nocturnal hemoglobinuria (PNH) is a rare disease presenting with variable and various clinical findings. PNH might be overlooked and diagnosis may be delayed due to low awareness about PNH. This is the first multicenter study in Turkey, investigating the efficiency of diagnostic screening of PNH by multiparameter flow cytometry (FCM) according to consensus guidelines.