Single photon emission computed tomography in adrenoleukodystrophy - A case report

Dirik E., Durak H., Eroglu Y., Sayit E., Buyukgebiz B.

TURKISH JOURNAL OF PEDIATRICS, cilt.38, sa.3, ss.349-353, 1996 (SCI-Expanded) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 38 Sayı: 3
  • Basım Tarihi: 1996
  • Dergi Adı: TURKISH JOURNAL OF PEDIATRICS
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Sayfa Sayıları: ss.349-353
  • Anahtar Kelimeler: adrenoleukodystrophy, magnetic resonance imaging, SPECT neuroimaging
  • Dokuz Eylül Üniversitesi Adresli: Hayır

Özet

Adrenoleukodystrophy (ALD) is a genetic disorder leading to progressive dysfunction of the adrenal cortex and nervous system white matter. Accumulation of fatty acids in cerebral white matter results in some anatomical and functional changes which are detectable by imaging studies. Lately, single photon emission computed tomography (SPECT) has been suggested for evaluation of cerebral perfusion changes. In this report, magnetic resonance imaging (MRI) and SPECT neuroimaging of an eight-year-old boy with ALD are presented. SPECT revealed more extensive involvement than that demonstrated by MRI. Its role in early prediction of the extention of disease is stressed.