Coenzyme Q(10) treatment reduces lipid peroxidation, inducible and endothelial nitric oxide synthases, and germ cell-specific apoptosis in a rat model of testicular ischemia/reperfusion injury


Erol B., BOZLU M., HANCI V., Tokgoz H., Bektas S., Mungan G.

FERTILITY AND STERILITY, vol.93, no.1, pp.280-282, 2010 (SCI-Expanded) identifier identifier identifier

  • Publication Type: Article / Editorial Material
  • Volume: 93 Issue: 1
  • Publication Date: 2010
  • Doi Number: 10.1016/j.fertnstert.2009.07.981
  • Journal Name: FERTILITY AND STERILITY
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Page Numbers: pp.280-282
  • Dokuz Eylül University Affiliated: No

Abstract

In this experimental study, we assessed the preventive effects of coenzyme Q(10) (CoQ(10)) in a rat model of ischemia/reperfusion injury. The results of this study show that CoQ(10) administration before the reperfusion period of testicular torsion provides a significant decrease in testicular lipid peroxidation products and expressions of inducible nitric oxide synthase, endothelial nitric oxide synthase, and germ cell-specific apoptosis. (Fertil Steril(R) 2010;93:280-2. (C)2010 by American Society for Reproductive Medicine.)