Coenzyme Q(10) treatment reduces lipid peroxidation, inducible and endothelial nitric oxide synthases, and germ cell-specific apoptosis in a rat model of testicular ischemia/reperfusion injury

Erol, Bulent; BOZLU, MURAT; HANCI, VOLKAN; Tokgoz, Husnu; Bektas, Sibel; Mungan, Gorkem

doi:10.1016/j.fertnstert.2009.07.981

Coenzyme Q(10) treatment reduces lipid peroxidation, inducible and endothelial nitric oxide synthases, and germ cell-specific apoptosis in a rat model of testicular ischemia/reperfusion injury

Erol B., BOZLU M., HANCI V., Tokgoz H., Bektas S., Mungan G.

FERTILITY AND STERILITY, cilt.93, sa.1, ss.280-282, 2010 (SCI-Expanded, Scopus)

Yayın Türü: Makale / Editöre Mektup
Cilt numarası: 93 Sayı: 1
Basım Tarihi: 2010
Doi Numarası: 10.1016/j.fertnstert.2009.07.981
Dergi Adı: FERTILITY AND STERILITY
Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
Sayfa Sayıları: ss.280-282
Dokuz Eylül Üniversitesi Adresli: Hayır

Özet

In this experimental study, we assessed the preventive effects of coenzyme Q(10) (CoQ(10)) in a rat model of ischemia/reperfusion injury. The results of this study show that CoQ(10) administration before the reperfusion period of testicular torsion provides a significant decrease in testicular lipid peroxidation products and expressions of inducible nitric oxide synthase, endothelial nitric oxide synthase, and germ cell-specific apoptosis. (Fertil Steril(R) 2010;93:280-2. (C)2010 by American Society for Reproductive Medicine.)