Indian Journal of Animal Research, cilt.59, sa.10, ss.1641-1646, 2025 (SCI-Expanded, Scopus)
Background: Various tranquilizers and anesthetics are frequently used in horses for both ophthalmic and other examinations and many surgical procedures. Many tranquilizers and anesthetics increase intraocular pressure and tear volume. This study aimed to determine the effects of three different anesthetic protocols frequently preferred in horses on intraocular pressure and tear volume. Methods: These horses were divided into 3 groups, each consisting of 6 horses. Group I (AXK) was administered 0.05 mg/kg Acepromazine, 1.1 mg/kg Xylazine HCl and 2.2 mg/kg Ketamine HCl, Group II (XK) was administered 1.1 mg/kg Xylazine HCl and 2.2 mg/kg Ketamine HCl, Group III (DK) was administered 0.03 mg/kg Dexmedetomidine HCl and 2.2 mg/kg Ketamine HCl intravenously. Tear volume, intraocular pressure, heart rate and respiratory rate and rectal body temperature were measured and recorded in all horses constituting the groups before premedication, at 5th and 20th minute and after recovery from anesthesia. Result: From the study, it was determined that intraocular pressure decreased in all three groups during anesthesia, with slight increase in tear volume, but the data obtained were within the reference ranges. As a result, it is suggested that the three anesthesia procedures evaluated in this study can be used in ocular surgery in horses and in operative procedures of patients with high intraocular pressure.