Dose conversion ratio, comparative efficacy, and adverse events after switching from onabotulinum toxin A to abobotulinum toxin A for neurological conditions

Ozer, İNCİ; Kumcu, Muge; Aydemir, Sabiha; AKBOSTANCI, MUHİTTİN

doi:10.1016/j.clineuro.2021.106889

Dose conversion ratio, comparative efficacy, and adverse events after switching from onabotulinum toxin A to abobotulinum toxin A for neurological conditions

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Ozer İ. Ş., Kumcu M. K., Aydemir S. T., AKBOSTANCI M. C.

CLINICAL NEUROLOGY AND NEUROSURGERY, vol.209, 2021 (SCI-Expanded)

Publication Type: Article / Article
Volume: 209
Publication Date: 2021
Doi Number: 10.1016/j.clineuro.2021.106889
Journal Name: CLINICAL NEUROLOGY AND NEUROSURGERY
Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus, Academic Search Premier, CAB Abstracts, EMBASE, MEDLINE
Keywords: Abobotulinum toxin A, Onabotulinum toxin A, Dystonia, Dysport, Botox, Dose conversion ratio, CERVICAL DYSTONIA, RETROSPECTIVE EVALUATION, DOUBLE-BLIND, DYSPORT, BOTOX, BLEPHAROSPASM, MANAGEMENT
Dokuz Eylül University Affiliated: Yes

Abstract

Objectives: Onabotulinum toxin A (ONA, Botox (R)) and abobotulinum toxin A (ABO, Dysport (R)) are most frequently used in the treatment of movement disorders. The aim of this study was to identify the dose conversion ratio (ABO dose:ONA dose), comparative efficacy, and adverse events in patients who switched from ONA to ABO.