Significance of heat shock protein-27 expression in patients with renal cell carcinoma

Erkizan O., Kirkali G., Yorukoglu K., Kirkali Z.

UROLOGY, vol.64, no.3, pp.474-478, 2004 (SCI-Expanded) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 64 Issue: 3
  • Publication Date: 2004
  • Doi Number: 10.1016/j.urology.2004.04.017
  • Journal Name: UROLOGY
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Page Numbers: pp.474-478
  • Dokuz Eylül University Affiliated: Yes

Abstract

Objectives. To investigate heat shock protein (HSP)-27 expression in patients with renal cell carcinoma (RCC) and examine its biologic significance. HSPs were first defined as proteins induced by heat shock and other environmental and pathophysiologic stresses. They are implicated in protein-protein interactions and are thought to play an important role in cancer. The expression of HSP-27 has been demonstrated in some human tumors.