Significance of heat shock protein-27 expression in patients with renal cell carcinoma

Erkizan O., Kirkali G., Yorukoglu K., Kirkali Z.

UROLOGY, cilt.64, sa.3, ss.474-478, 2004 (SCI-Expanded, Scopus) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 64 Sayı: 3
  • Basım Tarihi: 2004
  • Doi Numarası: 10.1016/j.urology.2004.04.017
  • Dergi Adı: UROLOGY
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Sayfa Sayıları: ss.474-478
  • Dokuz Eylül Üniversitesi Adresli: Evet

Özet

Objectives. To investigate heat shock protein (HSP)-27 expression in patients with renal cell carcinoma (RCC) and examine its biologic significance. HSPs were first defined as proteins induced by heat shock and other environmental and pathophysiologic stresses. They are implicated in protein-protein interactions and are thought to play an important role in cancer. The expression of HSP-27 has been demonstrated in some human tumors.