Frontal delta event-related oscillations relate to frontal volume in mild cognitive impairment and healthy controls

Yener G., Emek-Savas D. D., Lizio R., Cavusoglu B., Carducci F., ADA E., ...More

INTERNATIONAL JOURNAL OF PSYCHOPHYSIOLOGY, vol.103, pp.110-117, 2016 (SCI-Expanded, SSCI, Scopus) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 103
  • Publication Date: 2016
  • Doi Number: 10.1016/j.ijpsycho.2015.02.005
  • Journal Name: INTERNATIONAL JOURNAL OF PSYCHOPHYSIOLOGY
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Social Sciences Citation Index (SSCI), Scopus
  • Page Numbers: pp.110-117
  • Keywords: Event-related, Oscillations, EEG, MRI, Frontal, Volumetry, Delta, MCI, Alzheimer, Dementia
  • Dokuz Eylül University Affiliated: Yes

Abstract

Amnesic mild cognitive impairment (MCI) represents a risk of developing Alzheimer's disease (AD), but not all MCI subjects progress to dementia of AD type. Magnetic resonance imaging (MRI) of cortical and hippocampal atrophy supports early diagnosis of AD in MCI subjects, while frontal event-related oscillations (EROS) at delta frequencies (<4 Hz) are appealing markers for this purpose, as they are both cost-effective and largely available. The present study tested the hypothesis that these EROs reflect cortical frontal neurodegeneration in the continuum between normal and amnesic MCI subjects.