Morinda Citrifolia (Noni) and Low Dose Aspirin Prevent Apoptotic Cell Death and Oxidative Stress on Isoproterenol Induced Myocardial Infarction in Rats
Erciyes Tıp Dergisi/Erciyes Medical Journal, vol.39, 2017 (Peer-Reviewed Journal)
- Publication Type: Article / Article
- Volume: 39
- Publication Date: 2017
- Doi Number: 10.5152/etd.2017.1732
- Journal Name: Erciyes Tıp Dergisi/Erciyes Medical Journal
- Journal Indexes: Other Indexes
- Keywords: Aspirin, cathepsin B, caspase-3, catalase, Morinda citrifolia (noni), SOD
- Dokuz Eylül University Affiliated: No
Abstract
Objective: Isoproterenol (iso)-induced myocardial infarction is a widely used experimental model to study the beneficial effects of many drugs. Morinda citrifolia (noni) has traditionally been used for treating many diseases. Low-dose aspirin may have been protected heart tissueThis study aimed to investigate the possible protective effects of noni (20%) and low-dose aspirin (30 mg/kg) against iso-induced acute myocardial infarction in male Wistar rats.