Morinda Citrifolia (Noni) and Low Dose Aspirin Prevent Apoptotic Cell Death and Oxidative Stress on Isoproterenol Induced Myocardial Infarction in Rats

KUŞAT K., KANBAK G., OĞLAKÇI İLHAN A., KARTKAYA K., ERDEN İNAL M.

Erciyes Tıp Dergisi/Erciyes Medical Journal, cilt.39, 2017 (Hakemli Dergi) identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 39
  • Basım Tarihi: 2017
  • Doi Numarası: 10.5152/etd.2017.1732
  • Dergi Adı: Erciyes Tıp Dergisi/Erciyes Medical Journal
  • Derginin Tarandığı İndeksler: Other Indexes
  • Anahtar Kelimeler: Aspirin, cathepsin B, caspase-3, catalase, Morinda citrifolia (noni), SOD
  • Dokuz Eylül Üniversitesi Adresli: Hayır

Özet

Objective: Isoproterenol (iso)-induced myocardial infarction is a widely used experimental model to study the beneficial effects of many drugs. Morinda citrifolia (noni) has traditionally been used for treating many diseases. Low-dose aspirin may have been protected heart tissueThis study aimed to investigate the possible protective effects of noni (20%) and low-dose aspirin (30 mg/kg) against iso-induced acute myocardial infarction in male Wistar rats.