Purpose Precise extraction of aorta and the vessels departing from it (i.e. coeliac, renal, and iliac) is vital for correct positioning of a graft prior to abdominal aortic surgery. To perform this task, most of the segmentation algorithms rely on seed points, and better-located seed points provide better initial positions for cross-sectional methods. Under non-optimal acquisition characteristics of daily clinical routine and complex morphology of these vessels, inserting seed points to all these small, but critically important vessels is a tedious, time-consuming, and error-prone task. Thus, in this paper, a novel strategy is developed to generate pathways between user-inserted seed points in order to initialize segmentation methods effectively.