Increased adipsin is associated with carotid intima media thickness and metabolic disturbances in polycystic ovary syndrome.


Calan Ö., Calan M., Senses P. Y., Kocabas G. U., Ozden E., Sari K. R., ...More

Clinical endocrinology, vol.85, no.6, pp.910-917, 2016 (SCI-Expanded, Scopus)

  • Publication Type: Article / Article
  • Volume: 85 Issue: 6
  • Publication Date: 2016
  • Doi Number: 10.1111/cen.13157
  • Journal Name: Clinical endocrinology
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Page Numbers: pp.910-917
  • Dokuz Eylül University Affiliated: Yes

Abstract

ContextAdipsin, a protein secreted mainly from the adipose tissue, is a structural homologous of complement factor D, a rate-limiting enzyme of the alternative complement system. Growing evidence suggests that the alternative complement system plays a role both in the regulation of energy homoeostasis and in the atherosclerosis. Polycystic ovary syndrome (PCOS) is a reproductive and metabolic disease.