Increased adipsin is associated with carotid intima media thickness and metabolic disturbances in polycystic ovary syndrome.

Calan, ÖZLEM; Calan, Mehmet; Senses, Pinar; Kocabas, Gokcen; Ozden, Ebru; Sari, Kerime; Kocar, Merve; Imamoglu, Cetin; Senses, Yasar; Bozkaya, Giray; Bilgir, Oktay

doi:10.1111/cen.13157

Increased adipsin is associated with carotid intima media thickness and metabolic disturbances in polycystic ovary syndrome.

Calan Ö., Calan M., Senses P. Y., Kocabas G. U., Ozden E., Sari K. R., ...More

Clinical endocrinology, vol.85, no.6, pp.910-917, 2016 (SCI-Expanded, Scopus)

Publication Type: Article / Article
Volume: 85 Issue: 6
Publication Date: 2016
Doi Number: 10.1111/cen.13157
Journal Name: Clinical endocrinology
Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
Page Numbers: pp.910-917
Dokuz Eylül University Affiliated: Yes

Abstract

ContextAdipsin, a protein secreted mainly from the adipose tissue, is a structural homologous of complement factor D, a rate-limiting enzyme of the alternative complement system. Growing evidence suggests that the alternative complement system plays a role both in the regulation of energy homoeostasis and in the atherosclerosis. Polycystic ovary syndrome (PCOS) is a reproductive and metabolic disease.