Is ketogenic diet treatment hepatotoxic for children with intractable epilepsy?

ARSLAN N., Guzel O., Kose E., Yilmaz U., Kuyum P., Aksoy B., ...More

SEIZURE-EUROPEAN JOURNAL OF EPILEPSY, vol.43, pp.32-38, 2016 (SCI-Expanded, Scopus)

  • Publication Type: Article / Article
  • Volume: 43
  • Publication Date: 2016
  • Doi Number: 10.1016/j.seizure.2016.10.024
  • Journal Name: SEIZURE-EUROPEAN JOURNAL OF EPILEPSY
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Page Numbers: pp.32-38
  • Keywords: Aminotransferase, Children, Epilepsy, Fatty liver, Gallstone, Ketogenic diet
  • Dokuz Eylül University Affiliated: Yes

Abstract

Purpose: Long-term ketogenic diet (IUD) treatment has been shown to induce liver steatosis and gallstone formation in some in vivo and clinical studies. The aim of this retrospective study was to evaluate the hepatic side effects of KD in epileptic children.