Successful therapy with rituximab of refractory acute humoral renal transplant rejection: A case report

Celik A., Saglarn F., Cavdar C., Sifil A., ATİLA K., SARIOĞLU S., ...Daha Fazla

TRANSPLANTATION PROCEEDINGS, cilt.40, sa.1, ss.302-304, 2008 (SCI-Expanded) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 40 Sayı: 1
  • Basım Tarihi: 2008
  • Doi Numarası: 10.1016/j.transproceed.2007.11.011
  • Dergi Adı: TRANSPLANTATION PROCEEDINGS
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Sayfa Sayıları: ss.302-304
  • Dokuz Eylül Üniversitesi Adresli: Evet

Özet

Acute humoral rejection (AHR) is generally less responsive to conventional anti-rejection treatment with consequent allograft losses. Therapeutic options include antilymphocyte antibody (ATG), intravenous immunglobulin (IVIG), plasmapheresis, or immunoadsorption with protein A together with intensification of immunsuppression with a tacrolimus/mycophenolate mofetil combination. This report describes a transplant recipient who responded to rituximab therapy as treatment for steroid-, ATG-, IVIG-, and plasmapheresis-resistant AHR.