Role of fecal calprotectin in the assessment of intestinal inflammation in children with familial Mediterranean fever

Gucenmez O. A., KÜME T., Makay B., Babayigit O., ARSLAN N., Unsal E.

INTERNATIONAL JOURNAL OF RHEUMATIC DISEASES, cilt.21, sa.10, ss.1844-1848, 2018 (SCI-Expanded) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 21 Sayı: 10
  • Basım Tarihi: 2018
  • Doi Numarası: 10.1111/1756-185x.13396
  • Dergi Adı: INTERNATIONAL JOURNAL OF RHEUMATIC DISEASES
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Sayfa Sayıları: ss.1844-1848
  • Anahtar Kelimeler: Calprotectin, familial Mediterranean fever, gastrointestinal inflammation, BOWEL-DISEASE, ASSOCIATION, MUTATIONS, CRITERIA, MARKER
  • Dokuz Eylül Üniversitesi Adresli: Evet

Özet

Aim: Familial Mediterranean fever (FMF) is the most common auto-inflammatory disease with recurrent fever and serositis episodes. In recent years, some cases with FMF were reported with gastrointestinal involvement without amyloidosis, vasculitis and inflammatory bowel disease (IBD). It is not yet known whether gastrointestinal involvement is a part of the disease or not. The aim of this study is to investigate the frequency of intestinal inflammation by using a noninvasive method, fecal calprotectin measurement, in pediatric FMF patients.