Cerebral Hemodynamics and Incident Depression: The Rotterdam Study

Direk, Nese; Koudstaal, Peter; Hofman, Albert; Ikram, M.; Hoogendijk, Witte; Tiemeier, Henning

doi:10.1016/j.biopsych.2012.01.019

Cerebral Hemodynamics and Incident Depression: The Rotterdam Study

Direk N., Koudstaal P. J., Hofman A., Ikram M. A., Hoogendijk W. J., Tiemeier H.

BIOLOGICAL PSYCHIATRY, vol.72, no.4, pp.318-323, 2012 (SCI-Expanded, Scopus)

Publication Type: Article / Article
Volume: 72 Issue: 4
Publication Date: 2012
Doi Number: 10.1016/j.biopsych.2012.01.019
Journal Name: BIOLOGICAL PSYCHIATRY
Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
Page Numbers: pp.318-323
Keywords: Blood flow velocity, geriatric depression, incident depression, subthreshold depression, vascular depression, vasomotor reactivity
Dokuz Eylül University Affiliated: No

Abstract

Background: According to the vascular depression hypothesis, subclinical cerebrovascular disease can cause depression in older adults. To test this hypothesis, several cross-sectional studies have assessed structural brain parameters, but few have examined hemodynamic alterations in the brain.