Cadmium in bone cement induces necrosis and decreases the viability of residual osteosarcoma cells: A xenograft study

Demirkiran N. D., AKTAŞ S., Ozdemir A. P. E., Bekcioglu O., Aydin M., HAVITÇIOĞLU H.

ACTA ORTHOPAEDICA ET TRAUMATOLOGICA TURCICA, cilt.54, sa.4, ss.445-452, 2020 (SCI-Expanded) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 54 Sayı: 4
  • Basım Tarihi: 2020
  • Doi Numarası: 10.5152/j.aott.2020.20247
  • Dergi Adı: ACTA ORTHOPAEDICA ET TRAUMATOLOGICA TURCICA
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus, EMBASE, MEDLINE, Directory of Open Access Journals, TR DİZİN (ULAKBİM)
  • Sayfa Sayıları: ss.445-452
  • Anahtar Kelimeler: Cadmium, Cement, Xenograft, Osteosarcoma, LOCAL RECURRENCE, CALCIUM, ROS, CHEMOTHERAPY, MANAGEMENT, TOXICITY
  • Dokuz Eylül Üniversitesi Adresli: Evet

Özet

Objective: The aim of this study was to show whether local application of cadmium-impregnated bone cement can induce apoptosis and decrease the viability of residual osteosarcoma (OS) cells in nude mice.