Chemotherapy-induced acral erythema in a pediatric patient with acute monoblastic leukemia

Demircioglu F., ÖREN H., YILMAZ Ş., Arslansoyu S., Eren S., Irken G.

PEDIATRIC HEMATOLOGY AND ONCOLOGY, cilt.25, sa.3, ss.211-215, 2008 (SCI-Expanded) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 25 Sayı: 3
  • Basım Tarihi: 2008
  • Doi Numarası: 10.1080/08880010801938157
  • Dergi Adı: PEDIATRIC HEMATOLOGY AND ONCOLOGY
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Sayfa Sayıları: ss.211-215
  • Anahtar Kelimeler: acute monoblastic leukemia, chemotherapy-induced acral erythema, children, DOSE CYTOSINE-ARABINOSIDE, METHOTREXATE, CYTARABINE, CHILDHOOD
  • Dokuz Eylül Üniversitesi Adresli: Evet

Özet

Chemotherapy-induced acral erythema or palmoplantar erythrodysesthesia syndrome is a well-defined reaction to some of the chemotherapeutic agents such as methotrexate, cytarabine, doxorubicin, fluorouracil, and bleomycin. This reaction is characterized by symmetrical, well-demarcated, painful erythema of the palms and soles, which may progress to desquamation. The authors present a case of acral erythema in a young patient with acute monoblastic leukemia to emphasize this high-dose chemotherapy-induced side effect, which is rarely seen in children and is usually self-limited.