Determination of a Sample-to-Cutoff Ratio to Predict True-Positivity in Blood Donor Samples Screened for Syphilis by a Chemiluminescent Immunoassay

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Akcakanat I. E., Özbek Ö. A., Doğan Y., Abacioglu Y. H.

JOURNAL OF BASIC AND CLINICAL HEALTH SCIENCES, cilt.2, sa.1, ss.1-6, 2018 (Hakemli Dergi) identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 2 Sayı: 1
  • Basım Tarihi: 2018
  • Doi Numarası: 10.30621/jbachs.2018.277
  • Dergi Adı: JOURNAL OF BASIC AND CLINICAL HEALTH SCIENCES
  • Sayfa Sayıları: ss.1-6
  • Anahtar Kelimeler: Syphilis, architect syphilis, transfusion-transmitted disease, reverse sequence, TREPONEMA-PALLIDUM, WESTERN-BLOT, ANTIBODIES, REACTIVITY, GUIDELINES, MANAGEMENT, DIAGNOSIS, TURKEY, ASSAY
  • Dokuz Eylül Üniversitesi Adresli: Evet

Özet

Purpose: The use of Architect Syphilis TP (CMIA) in the blood bank raised the number of syphilis positive samples requiring confirmation. The aim of this study is to determine a sample-to-cutoff (s/co) ratio for CMIA predicting >= 95% of true-positive samples to reduce these samples.