Role of mesenchymal stem cell-derived soluble factors and folic acid in wound healing

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Pakdemirli A., Toksoz F., Karadag A., Misirlioglu H. K., Başbınar Y., Ellidokuz H., ...More

TURKISH JOURNAL OF MEDICAL SCIENCES, vol.49, no.3, pp.914-921, 2019 (SCI-Expanded) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 49 Issue: 3
  • Publication Date: 2019
  • Doi Number: 10.3906/sag-1901-231
  • Journal Name: TURKISH JOURNAL OF MEDICAL SCIENCES
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus, TR DİZİN (ULAKBİM)
  • Page Numbers: pp.914-921
  • Keywords: Mesenchymal stem cell, mesenchymal stem cell-derived soluble factor, wound healing, folic acid, cell differentiation, REPAIR
  • Dokuz Eylül University Affiliated: Yes

Abstract

Background/aim: Mesenchymal stem cells (MSCs) are a type of adult stem cell consisting of a heterogeneous subset of stromal stem cells that can be isolated from adult tissues. Folic acid is another important contributor to tissue regeneration and repair, which affects the synthesis of some building block molecules used for wound healing. In this study, we examine the effect of folic acid and MSC-derived soluble factors in the wound healing model.