Erythropoietin restores bowel damage and hypoperistalsis in gastroschisis

Ozdamar A., Topcu K., Gumustekin M., Gurel D., Gelal A., Ozer E., ...Daha Fazla

JOURNAL OF PEDIATRIC SURGERY, cilt.41, sa.2, ss.352-357, 2006 (SCI-Expanded) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 41 Sayı: 2
  • Basım Tarihi: 2006
  • Doi Numarası: 10.1016/j.jpedsurg.2005.11.012
  • Dergi Adı: JOURNAL OF PEDIATRIC SURGERY
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Sayfa Sayıları: ss.352-357
  • Anahtar Kelimeler: gastroschisis, erythropoietin, gastrointestinal contractility, ALLANTOIC FLUID EXCHANGE, INTESTINAL DAMAGE, NECROTIZING ENTEROCOLITIS, RABBIT MODEL, CONTRACTILITY, PREVENTION, ETIOLOGY, INFANTS
  • Dokuz Eylül Üniversitesi Adresli: Evet

Özet

Background and Purpose: Despite the decreased mortality in gastroschisis (Gx), patients experience postoperative intestinal hypoperistalsis, malabsorption, and shortened bowel length. The trophic effects of recombinant human erythropoietin (rEpo) in the developing small bowel have been reported, p increasing the length and height of the villi, and villous surface area. This study investigated the effects of rEpo on intestinal malfunction in the chick embryos with Gx.