Vasculitis and long standing ankylosing spondylitis in a patient with familial Mediterranean fever

Taylan A., Yildiz Y., SARI İ., Ozkok G.

Journal of Research in Medical Sciences, cilt.19, sa.10, ss.1009-1011, 2014 (SCI-Expanded, Scopus) identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 19 Sayı: 10
  • Basım Tarihi: 2014
  • Dergi Adı: Journal of Research in Medical Sciences
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Sayfa Sayıları: ss.1009-1011
  • Anahtar Kelimeler: Ankylosing spondylitis, familial Mediterranean fever, leukocytoklastic vasculitis, vasculitis
  • Dokuz Eylül Üniversitesi Adresli: Evet

Özet

Coexistence of familial Mediterranean fever (FMF) and other inflammatory disorders has been frequently reported, but no specific underlying factor has been identified. We report a patient with FMF who is presented with long-standing ankylosing spondylitis (AS) and cutaneous leukocytoklastic vasculitis (LV) of the lower limbs. It is the first report on combination of FMF with AS and LV. The Mediterranean Fever (MEFV) gene mutation of heterozygote (R202Q/R726A) and HLA-B27 are detected in this case, and are believed to form genetic susceptibility to LV.