Comparison of atherogenic risk factors among poorly controlled and well-controlled adolescent phenylketonuria patients

Gunduz M., Cakar S., Kuyum P., Makay B., ARSLAN N.

CARDIOLOGY IN THE YOUNG, vol.26, no.5, pp.901-908, 2016 (SCI-Expanded) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 26 Issue: 5
  • Publication Date: 2016
  • Doi Number: 10.1017/s104795111500150x
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Page Numbers: pp.901-908
  • Keywords: Phenylketonuria, low-density lipoprotein cholesterol, high-density lipoprotein cholesterol, mean platelet volume, homocysteine, MEAN PLATELET VOLUME, DENSITY-LIPOPROTEIN CHOLESTEROL, CARDIOVASCULAR RISK, OBESE ADOLESCENTS, OXIDATIVE STRESS, FOLLOW-UP, PHENYLALANINE, DISEASE, PLASMA, HOMOCYSTEINE
  • Dokuz Eylül University Affiliated: Yes


Background Previous studies investigating the known risk factors of atherosclerosis in phenylketonuria patients have shown conflicting results. The primary aim of our study was to investigate the serum atherogenic markers in adolescent classical phenylketonuria patients and compare these parameters with healthy peers. The secondary aim was to compare these atherogenic markers in well-controlled and poorly controlled patients.