The Relationship Between Slow Coronary Flow and Angiotensin Converting Enzyme and ATIIR1 Gene Polymorphisms

Yalcin, Ahmet; KALAY, NİHAT; ÇAĞLAYAN, AHMET; Kayaalti, Fatma; Duran, Mustafa; Ozdogru, Ibrahim; İNANÇ, MEHMET; DOĞAN, ALİ; Basar, Emrullah; OĞUZHAN, ABDURRAHMAN

doi:10.1016/s0027-9684(15)30810-5

The Relationship Between Slow Coronary Flow and Angiotensin Converting Enzyme and ATIIR1 Gene Polymorphisms

Yalcin A. A., KALAY N., ÇAĞLAYAN A. O., Kayaalti F., Duran M., Ozdogru I., ...Daha Fazla

JOURNAL OF THE NATIONAL MEDICAL ASSOCIATION, cilt.101, sa.1, ss.40-45, 2009 (SCI-Expanded, Scopus)

Yayın Türü: Makale / Tam Makale
Cilt numarası: 101 Sayı: 1
Basım Tarihi: 2009
Doi Numarası: 10.1016/s0027-9684(15)30810-5
Dergi Adı: JOURNAL OF THE NATIONAL MEDICAL ASSOCIATION
Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
Sayfa Sayıları: ss.40-45
Dokuz Eylül Üniversitesi Adresli: Hayır

Özet

Objectives: Endothelial dysfunction in coronary arteries is the main pathogenetic mechanism in patients with slow coronary flow (SCF). Angiotensin converting enzyme (ACE) gene polymorphism has important effects on endothelial function. However, angiographic studies investigating the relation between the ACE and angiotensin II type 1 receptor (ATIIR1) insertion (I)/deletion (D) polymorphism and SCF is limited.