The Significance of Histopathologic Assessment in Bone Marrow Disease in Neuroblastoma

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Ekmekci S., Ince D., Olgun N., Ozer E.

TURKISH JOURNAL OF PATHOLOGY, vol.38, no.2, pp.99-105, 2022 (ESCI) identifier identifier

  • Publication Type: Article / Article
  • Volume: 38 Issue: 2
  • Publication Date: 2022
  • Doi Number: 10.5146/tjpath.2021.01556
  • Journal Name: TURKISH JOURNAL OF PATHOLOGY
  • Journal Indexes: Emerging Sources Citation Index (ESCI), Scopus, Academic Search Premier, EMBASE, MEDLINE, Directory of Open Access Journals, TR DİZİN (ULAKBİM)
  • Page Numbers: pp.99-105
  • Keywords: Bone marrow biopsy, Neuroblastoma, Metastasis, Tumor differentiation, Tumor percentage, PROGNOSTIC-SIGNIFICANCE, RISK, METASTASIS, CHILDREN
  • Dokuz Eylül University Affiliated: Yes

Abstract

Objective: Neuroblastoma (NB) is the most common extracranial solid tumor in children and is responsible for 12% of cancer-related deaths. The status of metastatic disease in the bone marrow (BM) is a predictor of poor outcome. The purpose of this study was to investigate the predictive significance of histopathological examination of BM in NB.