Helicobacter pylori infection in children with constitutional delay of growth and puberty

Buyukgebiz A., Dundar B., Bober E., Buyukgebiz B.

JOURNAL OF PEDIATRIC ENDOCRINOLOGY & METABOLISM, cilt.14, sa.5, ss.549-551, 2001 (SCI-Expanded, Scopus) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 14 Sayı: 5
  • Basım Tarihi: 2001
  • Doi Numarası: 10.1515/jpem.2001.14.5.549
  • Dergi Adı: JOURNAL OF PEDIATRIC ENDOCRINOLOGY & METABOLISM
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Sayfa Sayıları: ss.549-551
  • Anahtar Kelimeler: constitutional delay of growth and puberty, Helicobacter pylori infection
  • Dokuz Eylül Üniversitesi Adresli: Evet

Özet

Helicobacter pylori is a gastroduodenal pathogen strongly associated with chronic gastritis and duodenal ulceration. It is thought that H, pylori infection might be one of the causes of growth retardation in children. The aim of this study was to evaluate the seroprevalence of H, pylori in children with constitutional delay of growth and puberty (CDGP). H. pylori seropositivity was studied in 24 children with CDGP (22 M, 2 F) and 32 healthy age-matched children with normal pubertal development. Mean age of the children with CDGP was 14.53 +/- 1.12 yr and all of them had been diagnosed as CBGP after physical and laboratory assessment. H, pylori IgG positivity was detected in 16 of the 24 children with CDGP (66.6%) and 12 of 32 controls (37.5%) (p <0.05), This finding is consistent with the hypothesis that H, pylori infection could be one of the environmental factors causing CDGP.