Therapeutic plasma exchange in patients with thrombotic thrombocytopenic purpura: A retrospective multicenter study
TRANSFUSION AND APHERESIS SCIENCE, vol.48, no.3, pp.353-358, 2013 (SCI-Expanded, Scopus)
- Publication Type: Article / Article
- Volume: 48 Issue: 3
- Publication Date: 2013
- Doi Number: 10.1016/j.transci.2013.04.016
- Journal Name: TRANSFUSION AND APHERESIS SCIENCE
- Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
- Page Numbers: pp.353-358
- Keywords: Thrombotic thrombocytopenic purpura, Therapeutic plasma exchange, Fresh frozen plasma, Complete response
- Dokuz Eylül University Affiliated: No
Abstract
Thrombotic thrombocytopenic purpura (TIT) is a particular form of thrombotic microangiopathy typically characterized by thrombocytopenia, microangiopathic hemolytic anemia, fever, neurological abnormalities, and renal dysfunction. UP requires a rapid diagnosis and an adapted management in emergency. Daily sessions of therapeutic plasma exchange (TPE) remain the basis of management of UP. Also, UP is a rare disease that is fatal if it is not treated. TPE has resulted in excellent remission and survival rates in UP patients.