Fatty liver in obese children: prevalence and correlation with anthropometric measurements and hyperlipidemia

Arslan N., Buyukgebiz B., Ozturk Y., Cakmakci H.

TURKISH JOURNAL OF PEDIATRICS, vol.47, no.1, pp.23-27, 2005 (SCI-Expanded) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 47 Issue: 1
  • Publication Date: 2005
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Page Numbers: pp.23-27
  • Keywords: fatty liver, child, obesity, aminotransferase, lipids, NONALCOHOLIC STEATOHEPATITIS, HEPATITIS, DISEASE
  • Dokuz Eylül University Affiliated: Yes


The aim of this study was to evaluate the correlation of ultrasonography-proven fatty liver with liver functions, serum lipid levels and anthropometric measurements in children with exogenous obesity. Three hundred and twenty-two patients (183 girls, 56.8%) with a mean age of 11.4 +/- 3.2 years (4-18 years) who presented with the complaint of obesity were enrolled. In 38 (11.8%) patients, increased liver echogenicity resembling fatty liver was found (Group 1). The body mass index percentages of group 1 patients were significantly higher than of those without fatty liver (Group 2) (157.7 +/- 18.0 vs 151.3 +/- 17.8, p=0.038). Alanine and aspartate aminotransferase levels of group 1 patients were significantly higher than of group 2 (p=0.002 vs p=0.028, respectively). Triglyceride levels were significantly higher in group 1 patients (120.8 +/- 88.8 vs 100.5 +/- 58.5 mg/dl, p=0.044). In conclusion, ultrasonography is an easy and noninvasive method for the diagnosis of fatty liver in children with obesity. Body mass index and serum lipids were higher in group 1 patients. The diagnosis and early treatment of obesity in childhood is important for the prevention and better treatment of related complications. Thus, ultrasonography should be a part of the early evaluation of obese children.