Mortality Risk Assessment Using PRECISE-DAPT and DAPT Scores in Acute Coronary Syndrome: A Comparative Analysis


ALAK Ç., Özpelit E., Çırgamış D., abusharekh m., baris n.

Journal of updates in cardiovascular medicine, cilt.13, sa.2, ss.99-114, 2025 (Hakemli Dergi) identifier

Özet

Objectives: This study aimed to compare the data on mortality of the clinical scoring system that predicts the risk of ischemia-bleeding under dual therapy. Materials and Methods: The records of the patients were retrospectively examined through the hospital information system and archival records. The prepared case data registration form and the Morisky Medication Adherence scale drug compliance scale were filled out. With these data, the patients’ predicting bleeding complications in Patients Undergoing Stent Implantation and Subsequent dual antiplatelet therapy (PRECISE-DAPT) and DAPT scores were calculated. Results: A total of 260 patients were included in the study. The PRECISE-DAPT and DAPT scores were calculated for the patients with acute coronary syndrome. A total of 62 patients (23.8%), exhibited a PRECISE-DAPT score of ≥25. The number of patients with a DAPT score ≥2 was found to be 193 (74.2%). In terms of mortality, patients with PRECISE-DAPT ≥25 and those with PRECISE-DAPT <25 were compared with another group (score should be specified here), and mortality was significantly higher in the high-score group [p=0.001 odds ratio: 6.94 confidence interval: (3.53-13.62)]. Patients were divided into 4 groups based on PRECISE-DAPT and DAPT scores and compared with each other (PRECISE-DAPT <25 and DAPT ≥2, PRECISE-DAPT ≥25 and DAPT ≥2, PRECISE-DAPT <25 and DAPT <2, PRECISE-DAPT ≥25 and DAPT <2). Patients with a high PRECISE-DAPT score had a significantly higher mortality rate compared to those with a lower DAPT score (p<0.001). Conclusion: In our study, we discovered that the bleeding risk score was insufficient for predicting bleeding events, but it could identify high-risk patients in terms of mortality.