Metabolomic profiling in ankylosing spondylitis using time-of-flight mass spectrometry

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DOĞAN H. O., ŞENOL O., KARADAĞ A., Yildiz S. N.

CLINICAL NUTRITION ESPEN, vol.50, pp.124-132, 2022 (ESCI) identifier identifier

  • Publication Type: Article / Article
  • Volume: 50
  • Publication Date: 2022
  • Doi Number: 10.1016/j.clnesp.2022.06.011
  • Journal Name: CLINICAL NUTRITION ESPEN
  • Journal Indexes: Emerging Sources Citation Index (ESCI), Scopus, CAB Abstracts, EMBASE, Food Science & Technology Abstracts, MEDLINE, Veterinary Science Database
  • Page Numbers: pp.124-132
  • Keywords: Ankylosing spondylitis, Fatty acid, Metabolomics, Phosphatidylcholine, UPLC Q-TOF/MS, Plasma, BIOMARKERS
  • Dokuz Eylül University Affiliated: Yes

Abstract

Background & aims: Ankylosing spondylitis (AS) is an inflammatory disease associated with destructive changes in the skeleton and joints. The exact molecular mechanism of the disease has not been fully elucidated. This study aimed to determine metabolic differences between active AS patients and healthy controls to understand the molecular mechanism of AS.