Tirofiban-induced acute profound thrombocytopenia after primary angioplasty

Dursunoglu D., Taşköylü Ö., Gür S., SARI İ.

Asian Cardiovascular and Thoracic Annals, cilt.21, sa.1, ss.74-76, 2013 (Scopus) identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 21 Sayı: 1
  • Basım Tarihi: 2013
  • Doi Numarası: 10.1177/0218492312445142
  • Dergi Adı: Asian Cardiovascular and Thoracic Annals
  • Derginin Tarandığı İndeksler: Scopus
  • Sayfa Sayıları: ss.74-76
  • Anahtar Kelimeler: Angioplasty, Balloon, Coronary, Drug hypersensitivity, Platelet aggregation inhibitors, Thrombocytopenia, Tirofiban [supplementary concept]
  • Dokuz Eylül Üniversitesi Adresli: Evet

Özet

Glycoprotein IIb/IIIa inhibitors are used in the acute coronary syndromes and percutaneous coronary intervention as antiplatelet agents. However, these agents induce thrombocytopenia in approximately 1% to 5% of patients, and may lead to bleeding complications. Abciximab is associated with higher incidence of thrombocytopenia than eptifibatide and tirofiban. We describe a case of acute profound thrombocytopenia due to on tirofiban treatment in a patient who underwent primary angioplasty. © The Author(s) 2012.