JOURNAL OF ANIMAL AND PLANT SCIENCES-JAPS, cilt.35, sa.4, ss.1068-1075, 2025 (SCI-Expanded, Scopus)
The Orthohepevirus A strain of hepatitis E virus (HEV) is one of the world's leading zoonotic viruses and poses significant public health concerns. HEV susceptibility has been demonstrated in a wide range of animal species and have the capacity to transmit the virus to humans. However, the contribution of Orthohepevirus A serotypes to HEV epidemiology remains poorly understood. Blood serum samples were collected from 188 domestic animals from different farms selected by random sampling in Burdur province of T & uuml;rkiye. The animal group consisted of 22 horses, 22 donkeys, 30 sheep, 25 goats, 27 cattle, 35 cats and 27 dogs. An overall HEV seroprevalence of 4.79% was observed. The presence of HEV antibodies in goats, horses, and donkeys was detected for the first time in T & uuml;rkiye. Statistical tests performed to determine the difference between seropositivity rates according to animal species were found significant at p <= 0.05. Orthohepevirus A RNA was undetectable in all samples using gel-based nested RT-PCR. In this first report on HEV in farm animals in T & uuml;rkiye, the presence of HEV antibodies suggests that farm animals may have an important role in spreading infection.