Phthalocyanine-chalcone conjugates

Aribi F., Vey C., TOPKAYA TAŞKIRAN D., KOSTAKOĞLU S. T., Fournier-dit-Chabert J., Buyukeksi S. I., ...More

JOURNAL OF PORPHYRINS AND PHTHALOCYANINES, vol.20, pp.497-504, 2016 (SCI-Expanded) identifier identifier

  • Publication Type: Article / Article
  • Volume: 20
  • Publication Date: 2016
  • Doi Number: 10.1142/s1088424616500310
  • Journal Name: JOURNAL OF PORPHYRINS AND PHTHALOCYANINES
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Page Numbers: pp.497-504
  • Keywords: phthalocyanine, chalcone, photodynamic therapy, photosensitizer, vascular disruption, CLICK-CHEMISTRY, DESIGN, AGENTS, PORPHYRIN, CHLORIN
  • Dokuz Eylül University Affiliated: Yes

Abstract

A phthalocyanine-chalcone conjugate was previously reported to retain the full photodynamic activity of the phthalocyanine and a slightly lowered antivascular effect of the chalcone. Assuming that it was due to an insufficient release of the chalcone, we described here several grafting modes applied to the preparation of phthalocyanine-chalcone conjugates.