Simultaneous determination of ascorbic acid, epinephrine and uric acid at over-oxidized poly(p-aminophenol) film modified electrode

KOÇAK Ç. C., DURSUN Z.

JOURNAL OF ELECTROANALYTICAL CHEMISTRY, cilt.694, ss.94-103, 2013 (SCI-Expanded) identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 694
  • Basım Tarihi: 2013
  • Doi Numarası: 10.1016/j.jelechem.2013.02.006
  • Dergi Adı: JOURNAL OF ELECTROANALYTICAL CHEMISTRY
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Sayfa Sayıları: ss.94-103
  • Anahtar Kelimeler: Ascorbic acid, Epinephrine, Uric acid, p-Aminophenol, Polymerization, Overoxidized polymer, GLASSY-CARBON ELECTRODE, ELECTROCATALYTIC OXIDATION, CONDUCTING POLYMERS, DOPAMINE, NOREPINEPHRINE, INJECTION, ELECTROCHEMISTRY, CATECHOLAMINES, SEROTONIN
  • Dokuz Eylül Üniversitesi Adresli: Evet

Özet

A modified electrode was fabricated by over-oxidation of polymer film after electropolymerization of p-aminophenol on a bare glassy carbon surface. A higher catalytic activity was obtained for electrocatalytic oxidation of ascorbic acid (AA), epinephrine (EN), and uric acid (UA) in pH 7.4 phosphate buffer solution (PBS) at over oxidized poly(p-aminophenol) film modified glassy carbon electrode (Ox-PAP/GCE) due to an enhanced peak current and well-defined peak separations compared with both bare glassy carbon electrode (GCE) and poly(p-aminophenol) film modified GCE (PAP/GCE). The electrode surfaces were characterized by scanning electron microscopy (SEM) and Atomic Force Microscopy (AFM). Individual and simultaneous determination of AA, EN, and UA were carried out by differential pulse voltammetry. The detection limits were individually calculated for ascorbic acid, epinephrine, and uric acid as being 1.0 x 10(-6) M, 6.5 x 10(-9) M, and 1.8 x 10(-7) M, respectively. (c) 2013 Elsevier B.V. All rights reserved.