A new approach to the treatment of recurrent aphthous stomatitis with bioadhesive gels containing cyclosporine A solid lipid nanoparticles: in vivo/in vitro examinations

KARAVANA, SİNEM; GÖKÇE, EVREN; Rencber, Seda; ÖZBAL, SEDA; PEKÇETİN, ÇETİN; GÜNERİ, PELİN; Ertan, Gokhan

doi:10.2147/ijn.s36883

A new approach to the treatment of recurrent aphthous stomatitis with bioadhesive gels containing cyclosporine A solid lipid nanoparticles: in vivo/in vitro examinations

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KARAVANA S. Y., GÖKÇE E. H., Rencber S., ÖZBAL S., PEKÇETİN Ç., GÜNERİ P., ...More

INTERNATIONAL JOURNAL OF NANOMEDICINE, vol.7, pp.5693-5704, 2012 (SCI-Expanded)

Publication Type: Article / Article
Volume: 7
Publication Date: 2012
Doi Number: 10.2147/ijn.s36883
Journal Name: INTERNATIONAL JOURNAL OF NANOMEDICINE
Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
Page Numbers: pp.5693-5704
Keywords: SLNs, buccal application, wound healing, oral mucosal disease, PLACEBO-CONTROLLED TRIAL, DOUBLE-BLIND, RHEOLOGICAL CHARACTERIZATION, MUCOADHESIVE PROPERTIES, PERIODONTAL-DISEASE, CLINICAL-EVALUATION, POLYMERIC SYSTEMS, IN-VITRO, DELIVERY, ULCERATION
Dokuz Eylül University Affiliated: Yes

Abstract

Aim: To develop a suitable buccal bioadhesive gel formulation containing cyclosporine A solid lipid nanoparticles (CsA SLNs) for the treatment of recurrent aphthous stomatitis.