HGF/C-MET PATHWAY HAS A ROLE IN TESTICULAR DAMAGE IN DIABETES INDUCED BY STREPTOZOTOCIN


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Gumustekin M., Arici A., Micili S., Karaman M., Guneli M. E., Tekmen I.

ACTA ENDOCRINOLOGICA-BUCHAREST, vol.13, no.1, pp.17-22, 2017 (SCI-Expanded) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 13 Issue: 1
  • Publication Date: 2017
  • Doi Number: 10.4183/aeb.2017.17
  • Journal Name: ACTA ENDOCRINOLOGICA-BUCHAREST
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Page Numbers: pp.17-22
  • Keywords: diabetes, HGF/c-Met, insulin, testis, testicular damage, OXIDATIVE STRESS, RATS, EXPRESSION, FERTILITY, APOPTOSIS, PITUITARY, TESTES, AXIS
  • Dokuz Eylül University Affiliated: Yes

Abstract

Objective. The aim of the study was to investigate the role of Hepatocyte Growth Factor (HGF)/c-Met pathway in testicular damage provoked by streptozotocin (STZ)induced diabetes and the effects of insulin treatment on the HGF/c-Met pathway.