Evaluation of the effects of intra-arterial sugammadex and dexmedetomidine: an experimental study


HANCI V., ÖZBİLGİN Ş., ÖZBAL S., KAMACI ÖZOCAK G., Ates H., BOZTAŞ N., ...More

REVISTA BRASILEIRA DE ANESTESIOLOGIA, vol.66, no.5, pp.456-464, 2016 (SCI-Expanded) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 66 Issue: 5
  • Publication Date: 2016
  • Doi Number: 10.1016/j.bjane.2015.01.003
  • Journal Name: REVISTA BRASILEIRA DE ANESTESIOLOGIA
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Page Numbers: pp.456-464
  • Keywords: Sugammadex, Dexmedetomidine, Intra-arterial, Rabbit, Experimental, INTRA-ARTERIAL INJECTION, VASCULAR ENDOTHELIUM, DRUG INJECTIONS, THIOPENTONE, PROPOFOL, GANGRENE, DIAZEPAM, INJURY, HAND, ISCHEMIA
  • Dokuz Eylül University Affiliated: Yes

Abstract

Background: Intra-arterial injection of medications may cause acute and severe ischemia and result in morbidity and mortality. There is no information in the literature evaluating the arterial endothelial effects of sugammadex and dexmedetomidine. The hypothesis of our study is that sugammadex and dexmedetomidine will cause histological changes in arterial endothelial structure when administered intra-arterially.