Significance of COX-2 expression in human renal cell carcinoma

Tuna B., Yorukoglu K., Gurel D., Mungan U., Kirkali Z.

UROLOGY, cilt.64, sa.6, ss.1116-1120, 2004 (SCI-Expanded) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 64 Sayı: 6
  • Basım Tarihi: 2004
  • Doi Numarası: 10.1016/j.urology.2004.07.023
  • Dergi Adı: UROLOGY
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Sayfa Sayıları: ss.1116-1120
  • Dokuz Eylül Üniversitesi Adresli: Evet

Özet

Objectives. To evaluate the expression of cyclooxygenase-2 (COX-2) and its association with clinicopathologic parameters, and to investigate the relationships between COX-2 expression and inflammation and carcinogenesis in human renal cell carcinoma. COX-2 expression is associated with aggressive clinicopathologic parameters and an unfavorable prognosis in several human malignancies.