Significance of COX-2 expression in human renal cell carcinoma

Tuna B., Yorukoglu K., Gurel D., Mungan U., Kirkali Z.

UROLOGY, vol.64, no.6, pp.1116-1120, 2004 (SCI-Expanded, Scopus)

  • Publication Type: Article / Article
  • Volume: 64 Issue: 6
  • Publication Date: 2004
  • Doi Number: 10.1016/j.urology.2004.07.023
  • Journal Name: UROLOGY
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Page Numbers: pp.1116-1120
  • Dokuz Eylül University Affiliated: Yes

Abstract

Objectives. To evaluate the expression of cyclooxygenase-2 (COX-2) and its association with clinicopathologic parameters, and to investigate the relationships between COX-2 expression and inflammation and carcinogenesis in human renal cell carcinoma. COX-2 expression is associated with aggressive clinicopathologic parameters and an unfavorable prognosis in several human malignancies.