Comparison of the therapeutic effects of sildenafil citrate, heparin and neuropeptides in a rat model of acetic acid-induced gastric ulcer

Kalayci, Mehmet; KOÇDOR, MEHMET; KULOĞLU, TUNCAY; Sahin, Ibrahim; SARAÇ, MEHMET; AKSOY, AZİZ; Yardim, Meltem; DALKILIÇ, SEMİH; Gursu, Onur; Aydin, Suna; AKKOÇ, RAMAZAN; Ugras, Meltem; ARTAŞ, GÖKHAN; ÖZERCAN, İBRAHİM; UĞUR, KADER; AYDIN, SÜLEYMAN

doi:10.1016/j.lfs.2017.08.013

Comparison of the therapeutic effects of sildenafil citrate, heparin and neuropeptides in a rat model of acetic acid-induced gastric ulcer

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Kalayci M., KOÇDOR M. A., KULOĞLU T., Sahin I., SARAÇ M., AKSOY A., ...More

LIFE SCIENCES, vol.186, pp.102-110, 2017 (SCI-Expanded)

Publication Type: Article / Article
Volume: 186
Publication Date: 2017
Doi Number: 10.1016/j.lfs.2017.08.013
Journal Name: LIFE SCIENCES
Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
Page Numbers: pp.102-110
Keywords: Gastric ulcer, Sildenafil citrate, Heparin, Neuropeptide, Immunohistochemistry, GHRELIN, MUCOSAL, STRESS, DAMAGE, PROTECTION, OBESTATIN, HISTORY, STATE
Dokuz Eylül University Affiliated: Yes

Abstract

Aims: The purpose of our investigative work has been to determine whether there can be therapeutic roles in the administration of sildenafil citrate, heparin and several neuropeptides on an animal model where gastric ulcers were induced with acetic acid, and to compare their efficacy.