Fatty liver in childhood


ÖZTÜRK Y., Soylu O. B.

World Journal of Hepatology, vol.6, no.1, pp.33-40, 2014 (SCI-Expanded) identifier identifier

  • Publication Type: Article / Review
  • Volume: 6 Issue: 1
  • Publication Date: 2014
  • Doi Number: 10.4254/wjh.v6.i1.33
  • Journal Name: World Journal of Hepatology
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Page Numbers: pp.33-40
  • Keywords: Children, Chronic liver disease, Insulin resistance, Metabolic syndrome, Nonalcoholic fatty liver disease, Nonalcoholic steatohepatitis, Obesity
  • Dokuz Eylül University Affiliated: No

Abstract

Fatty liver is a growing health problem worldwide. It might evolve to nonalcoholic steatohepatitis, cirrhosis and cause hepatocellular carcinoma. This disease, which has increased because of eating habits, changes in food content and lifestyle, affffects people from childhood. The most important risk factors are obesity and insulin resistance. Besides these factors, gender, ethnicity, genetic predisposition and some medical problems are also important. Cirrhosis in children is rare but is reported. Nonalcoholic fatty liver disease (NAFLD) has no specific symptoms or signs but should be considered in obese children. NAFLD does not have a proven treatment. Weight loss with family based treatments is the most acceptable management. Exercise and an applicable diet with low glycemic index and appropriate calorie intake are preferred. Drugs are promising but not sufficient in children for today. © 2014 Baishideng Publishing Group Co., Limited.