Quantitative phytochemical analysis of Inula viscosa extracts from Izmir, Türkiye


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Erol A., Gökbayrak Ö., Aktaş S.

in: 5th International Eurasian Conference on Biological and Chemical Sciences (EurasianBioChem 2022), Prof Dr Muhittin Doğan, Editor, (EurasianBioChem 2022) Editor Prof Dr Muhittin Doğan , Ankara, pp.1810-1813, 2022

  • Publication Type: Book Chapter / Chapter Other Book
  • Publication Date: 2022
  • Publisher: (EurasianBioChem 2022) Editor Prof Dr Muhittin Doğan
  • City: Ankara
  • Page Numbers: pp.1810-1813
  • Editors: Prof Dr Muhittin Doğan, Editor
  • Dokuz Eylül University Affiliated: Yes

Abstract

Inula viscosa (L.) is one of the most used medicinal plants in countries of the Mediterranean region. I.viscosa

has been used for many years in folk medicine for its anti-inflammatory, antipyretic, antiseptic, and

antiphlogistic activities, and for different diseases. This study aimed to assay phytochemical analysis and

antioxidant activity from different parts and different methods of Inula viscosa extract. After 300 kg of plants

collected in September 2020 were separated as leaves, flowers, stems, and aerial parts. These different parts

were extracted by maceration method, using different solvents (50% ethanol, 70% ethanol, methanol, water)

and their % yield was calculated. Thus, it was decided to use the aerial parts of extract obtained by maceration

with 70% ethanol solvent for this study. After that, total phenolic compound, total flavonoid compound ratios,

and antioxidant activity were evaluated. Inula viscosa extract showed antioxidant activity and had a strong

correlation with total flavonoid content. Our future goals are to conduct in vitro, in-vivo, and ex-vivo

experiments of Inula viscosa, to elucidate its molecular mechanisms of action and to investigate its effects on

different diseases. Thanks to the increase in studies to be carried out on such medicinal plants, which are

frequently used among the public, it is thought that the side effects encountered because of misuse can be

minimized by preparing reliable, dose-specific, modern phytotherapeutic preparations. This project has the

code 2020.KB.MLT.005 and was supported by the Dokuz Eylül University,Department of Scientific Research

Project.